Cardiac arrest is a life-threatening emergency where the heart suddenly stops beating. It results from an electrical malfunction, causing an irregular rhythm or complete cessation of the heart's pumping action. Immediate medical attention is crucial as it severely impairs blood flow to vital organs, including the brain, leading to potential brain damage and death within minutes.
Therapeutic hypothermia, or targeted temperature management, is a medical intervention used to improve survival and minimize brain damage after cardiac arrest. It involves lowering the body's core temperature to 32°C (89.6°F) to 34°C (93.2°F) for about 24 hours. This mild hypothermia reduces brain inflammation, harmful chemical production, and metabolic processes. By protecting the brain, it enhances the chances of positive neurological outcomes and long-term survival after cardiac arrest.
A stroke happens when blood supply to the brain is interrupted or reduced, either by a blockage (ischemic stroke) or a blood vessel rupture (hemorrhagic stroke). This leads to rapid cell death due to oxygen and nutrient deprivation, causing various symptoms and complications depending on the affected brain area. Quick treatment is vital to minimize brain damage and enhance recovery prospects.
Therapeutic hypothermia, or targeted temperature management, aims to improve outcomes in patients with acute ischemic stroke. It involves lowering the body's core temperature to a specific target range for a defined period. Hypothermia therapy for stroke aims to reduce brain inflammation, metabolic rate, and secondary brain injury. By protecting brain tissue, minimizing harmful chemical release, and improving neurological outcomes, hypothermia offers potential benefits in stroke treatment.
Oral mucositis is inflammation and ulceration of the mouth and throat lining, often caused by cancer treatments like chemotherapy and radiation therapy. It leads to discomfort, pain, and difficulty in eating, swallowing, and speaking. The severity varies from mild redness to severe ulcers and bleeding, with an increased risk of infections. It typically occurs shortly after starting cancer treatment and may persist throughout or after treatment. Managing oral mucositis is crucial for improving quality of life and preventing complications.
Cryotherapy for oral mucositis involves applying cold temperatures to reduce its severity and duration. It constricts blood vessels, reducing blood flow and minimizing damage from chemotherapy or radiation. Cryotherapy aims to decrease inflammation, alleviate pain, and promote healing. Patients use cold treatment before, during, and after sessions to numb the mouth, enhance comfort, and facilitate eating, drinking, and oral hygiene.