Targeted temperature management (TTM) also known as therapeutic hypothermia is a medical intervention that carefully lowers and maintains a patient's body temperature for a specific period of time. It is used to protect the brain and vital organs from further damage by reducing metabolic activity and minimizing inflammation.

By lowering the body temperature, harmful processes can be slowed down, potentially improving patient outcomes. TTM is commonly applied after cardiac arrest, traumatic brain injury, or certain types of strokes.